Number of the records: 1
DNA adducts, p53 and p21WAF1 espression, and cell cycl alterations after exposure of embryonal human lung fibroblasts to PAHs
- 1.0173365 - UEM-P 20003089 RIV HU eng C - Conference Paper (international conference)
Giguere, Y. - Binková, Blanka - Rössner ml., Pavel - Dostál, Miroslav - Šrám, Radim
DNA adducts, p53 and p21WAF1 espression, and cell cycl alterations after exposure of embryonal human lung fibroblasts to PAHs.
Proceedings of the 30th Annual Meeting of European Environmental Mutagen Society. Budapest: EEMS, 2000, s. P150.
[Annual Meeting of EEMS /30./. Budapest (HU), 22.08.2000-26.08.2000]
R&D Projects: GA MŽP SI/340/2/00
Grant - others:EU(XE) (PHARE II, AC/HEA/18)
Institutional research plan: CEZ:AV0Z5039906
Subject RIV: DN - Health Impact of the Environment Quality
The effect of exposure to dibenzo[a,l]pyrene and benzo[a]pyrene in human diploid lung fibroblast cells was studied in an in vitro system using multiple end-points: DNA adduct levels were measured by 32P-postlabelling, the expression of p53 and p21 prooteins by western blotting and the cell cycle distribution by flow cytometry.
Permanent Link: http://hdl.handle.net/11104/0070399
Number of the records: 1