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Extracellular diffusion in the striatum of 6-ohda - lesioned and grafted rats

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    0173337 - UEM-P 20003060 RIV US eng C - Conference Paper (international conference)
    Olshausen, F. - Reum, T. - Mazel, Tomáš - Voříšek, Ivan - Morgenstern, R. - Syková, Eva
    Extracellular diffusion in the striatum of 6-ohda - lesioned and grafted rats.
    Society for Neuroscience. New Orleans: organizer, 2000, s. 870.
    [Annual Meeting /30./. New Orleans (US), 04.11.2000-09.11.2000]
    R&D Projects: GA ČR GV309/97/K048; GA ČR GA309/99/0657; GA MŠMT VS96130
    Institutional research plan: CEZ:AV0Z5039906
    Subject RIV: FH - Neurology

    We found a functional recovery, good survivalo of TH - positive cells and astrogliosis in grafted rats at 3 - 5 months after grafting.The increase in ECS diffusion barriers corresponded to the astrogliosis in and around the grafts. The increase in ECSS diffusion barriers corresponded to the astrogliosis in and around the grafts. The increase of extracellular tortuosity therefore suggests an impediment of DA diffusion from the gtrafts into the lesioned striatum.
    Permanent Link: http://hdl.handle.net/11104/0070372

     
     

Number of the records: 1  

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