Contractile properties, fiber types, and myosin isoforms in fast and slow muscles of hyperactive Japanese waltzing mice

0142554 - FGU-C 20030166 RIV US eng J - Journal Article
Asmussen, G. - Schmalbruch, I. - Soukup, Tomáš - Pette, D.
Contractile properties, fiber types, and myosin isoforms in fast and slow muscles of hyperactive Japanese waltzing mice.
Experimental Neurology. Roč. 184, č. 2 (2003), s. 758-766. ISSN 0014-4886. E-ISSN 1090-2430
R&D Projects: GA ČR GA304/00/1653
Grant - others:Deutsche Forschungsgemeinschaft(DE) -; Sonderforschungsbereich(DE) 156; Schwerpunkt Muskelforschung(DE) As 74/1-2
Institutional research plan: CEZ:AV0Z5011922
Keywords : Japanese waltzing mouse * muscle contraction * myosin isoforms
Subject RIV: ED - Physiology
Impact factor: 3.676, year: 2003

Our study of contractile properties, fiber type composition and myosin heavy chain isoform expression showed that the inherently enhanced motor activity of the Japanese waltzing mice (JWM) leads to fiber type transitions in the direction of slower phenotypes. JWM thus represent a suitable model for studying fast-to-slow fiber transitions under the influence of spontaneous motor hyperactivity.
Permanent Link: http://hdl.handle.net/11104/0040255