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The effect of nonsteroidal anti-inflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma
- 1.0126748 - BFU-R 20023047 RIV US eng J - Journal Article
Hoferová, Zuzana - Fedoročko, P. - Hofmanová, Jiřina - Hofer, Michal - Znojil, V. - Minksová, Kateřina - Souček, Karel - Egyed, A. - Kozubík, Alois
The effect of nonsteroidal anti-inflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma.
Cancer Investigation. Roč. 20, č. 4 (2002), s. 490-498. ISSN 0735-7907. E-ISSN 1532-4192
R&D Projects: GA AV ČR IBS5004009
Grant - others:VEGA MŠ SR(SK) 1/6026/99
Institutional research plan: CEZ:AV0Z5004920
Keywords : cyclooxygenase (COX) inhibitors * fibrosarcoma cells
Subject RIV: BO - Biophysics
Impact factor: 1.850, year: 2002
Three different cyclooxygenase (COX) inhibitors were found to inhibit growth of transplanted fibrosarcoma in mice. Their antitumor effect is supposed to comprise both direct action of COX inhibitors on fibrosarcoma cells and indirect effects that are presumably mediated by extratumoral sources.
Permanent Link: http://hdl.handle.net/11104/0024976
Number of the records: 1