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Transplants of cells engineered to produce GABA suppress spontaneous seizures

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    0102582 - FGU-C 20040019 RIV US eng J - Journal Article
    Thompson, K. W. - Suchomelová, Lucie
    Transplants of cells engineered to produce GABA suppress spontaneous seizures.
    [Transplantáty buněk se schopností produkovat GABA potlačují spontánní záchvaty.]
    Epilepsia. Roč. 45, č. 1 (2004), s. 4-12. ISSN 0013-9580. E-ISSN 1528-1167
    Grant - others:VA Greater Los Angeles Healthcare System Research Service(US) MREP
    Institutional research plan: CEZ:AV0Z5011922
    Keywords : cell transplantation * epilepsy * seizures
    Subject RIV: FH - Neurology
    Impact factor: 3.329, year: 2004

    The purpose of this study was to establish that cells genetically engineered to produce GABA could suppress spontaneous seizures in an accepted model of temporal lobe epilepsy. It was found that these cells have the ability to suppress above mentioned seizures when transplanted into seizure-modulating nuclei

    Cílem práce bylo určit na modelu temporální epilepsie, zda buňky vybavené pro produkci GABA, mohou potlačit spontánní záchvaty. Zjistili jsme, že při transplantaci těchto buněk do jader modulujících záchvaty, jsou záchvaty potlačeny
    Permanent Link: http://hdl.handle.net/11104/0009930

     
     

Number of the records: 1  

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