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No-effect level in the mutagenic activity of the drug cyproterone acetate in rat liver. Part I. Single dose treatment

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    0100983 - UEM-P 20043012 RIV NL eng J - Journal Article
    Topinka, Jan - Oesterle, D. - Reimann, R. - Wolff, T.
    No-effect level in the mutagenic activity of the drug cyproterone acetate in rat liver. Part I. Single dose treatment.
    [Neúčinná dávka pro mutagenní aktivitu cyproteronu acetátu v játrech potkanů.Část I. Jednorázová dávka.]
    Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. Roč. 550, 1-2 (2004), s. 89-99. ISSN 0027-5107. E-ISSN 1873-135X
    Institutional research plan: CEZ:AV0Z5039906
    Keywords : cyproterone acetate * DNA adducts
    Subject RIV: DN - Health Impact of the Environment Quality
    Impact factor: 3.730, year: 2004

    Our findings indicate that the lenght of the observation period may be a critical determinant for the outcome of a mutagensis study in rat liver. The existence of a no-effect level for the mutagenicity of CPA in rat liver was confirmed

    Naše zjištění ukazují, že pro výsledek studia mutagenního účinku CPA v játrech potkanů je určující doba sledování. Byla potvrzena neúčinná dávka pro mutagenicitu CPA v játrech potkanů
    Permanent Link: http://hdl.handle.net/11104/0008458
     

Number of the records: 1  

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