0100364 - MBU-M 20040054 RIV NL eng J - Journal Article
Opekarová, Miroslava - Tanner, W.
Specific lipid requirements of membrane proteins- a putative bottleneck in heterologous expression.
[Specifické požadavky membránových proteinů na lipidy – možná příčina omezení heterologní exprese.]
Biochimica Et Biophysica Acta-Biomembranes. Roč. 1610, - (2003), s. 11-22. ISSN 0005-2736. E-ISSN 1879-2642
R&D Projects: GA ČR GA204/02/1434
Grant - others:GA by the Deutsche Forschungsgemeinshaft(DE) SFB 521 and SPP 1108-TA36/17-1
Keywords : lipid requirements * cl * gpcr
Subject RIV: EE - Microbiology, Virology
Impact factor: 2.665, year: 2003

Membrane proteins are mostly protein-lipid complexes. With respect to specific lipid requirements of membrane proteins, the phospholipid and glycolipid as well as the sterol content of the host cell chosen for heterologous expression should be carefully considered. A few examples of heterologous expression of membrane proteins, where problems of specific lipid requirements have been noticed or should be thought of, have been chosen.

Membránové proteiny představují většinou komplexy s lipidy. V práci jsou diskutovány některé příklady heterologní exprese ve vztahu k požadavkům na složení lipidů.
Permanent Link: http://hdl.handle.net/11104/0007866