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Circadian rhythms in the rat intestine
- 1.0098755 - FGÚ 2008 ES eng A - Abstract
Soták, Matúš - Rybová, Markéta - Sládek, Martin - Polidarová, Lenka - Sumová, Alena - Pácha, Jiří
Circadian rhythms in the rat intestine.
[Cirkadiánní rytmy ve střevu potkana.]
Journal of Physiology and Biochemistry. Springer. Roč. 63, č. 1 (2007), s. 11-11. ISSN 1138-7548. E-ISSN 1877-8755.
[Meeting European Intestinal Transport Group /21./. 03.03.2007-06.03.2007, Oberwiesenthal]
R&D Projects: GA AV ČR(CZ) IAA500110605
Institutional research plan: CEZ:AV0Z50110509
Keywords : cpr1 * circadian * intestine * NHE3
Subject RIV: ED - Physiology
We have demostrated that gastrointestinal tract possess intrinsic molecular clockwork system which is partly independent on central clock. We have shown rhythmic circadian mRNA expression of clock genes Per1, Per2, Rev-Erb-alpha, Bmal1 and one clock controlled gene - NHE3 (Na+/H+ cotransporter) in the rat intestine
Ukázali jsme přítomnost molekulárního mechanizmu periférních vnitřnich hodin v trávicim traktu potkana. Byla stanovena cirkadiánní rytmická exprese mRNA tzv. hodinových genů a jednoho /"clock-controlled/" genu - kotransportéru Na+/H+, NHE3 ve střevu potkana
Permanent Link: http://hdl.handle.net/11104/0157580
Number of the records: 1