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Hypoxia-induced changes of seizure susceptibility in immature rats are modified by vigabatrin
- 1.0098023 - FGÚ 2008 RIV FR eng J - Journal Article
Kubová, Hana - Mareš, Pavel
Hypoxia-induced changes of seizure susceptibility in immature rats are modified by vigabatrin.
[Vigabatrin modifikuje změny záchvatové vnímavosti vyvolané hypoxií u mláďat potkana.]
Epileptic Disorders. Roč. 10, Suppl.1 (2007), s. 37-44. ISSN 1294-9361. E-ISSN 1950-6945
R&D Projects: GA ČR(CZ) GA304/05/2582
Institutional research plan: CEZ:AV0Z50110509
Keywords : immature brain * hypobaric hypoxia * vigabatrin
Subject RIV: ED - Physiology
Impact factor: 0.919, year: 2007
Exposure of 25-day-old rats to hypobaric hypoxia resulted in an increased susceptibility to pentetrazol-induced seizures and increased mortality 3 days after exposure. Vigabatrin was able to decrease moderately both these effects
Potkani ve věku 25 dnů vykazují 3 dny po exposici hypobarické hypoxie zvýšenou citlivost na záchvatyvyvolané pentetrazolem a zvýšenou mortalitu. Vigabatrin mírně (ale statisticky významně) oslaboval tyto účinky
Permanent Link: http://hdl.handle.net/11104/0157036
Number of the records: 1