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Relationship between Volatile Odorous Substances and Production of Avermectins by Streptomyces avermitilis

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    0085746 - MBÚ 2008 RIV SIGLE CZ eng J - Journal Article
    Řezanka, Tomáš - Sobotka, Miroslav - Prell, Aleš - Sigler, Karel
    Relationship between Volatile Odorous Substances and Production of Avermectins by Streptomyces avermitilis.
    [Vztah mezi těkavými pachovými látkami a produkcí avermektinů u Streptomyces avermitilis.]
    Folia Microbiologica. Roč. 52, č. 1 (2007), s. 26-30. ISSN 0015-5632. E-ISSN 1874-9356
    Institutional research plan: CEZ:AV0Z50200510
    Keywords : streptomyces avermitilis * antibiotics * inhibition
    Subject RIV: EE - Microbiology, Virology
    Impact factor: 0.989, year: 2007

    The time course of production of odorous compounds, i.e. geosmin and oxolones, and of avermectins was determined during the cultivation of S. avermitilis in flasks, 1- and 50-L fermentors. The amount of the antibiotics and geosmin increased with increasing cultivation time. A correlation was found between the production of geosmin and the production of avermectins. The production of oxolones peaked on cultivation days 3–5 and then it dropped below a measurable level. This can be explained as being due to the inhibition of oxolone production by geosmin.

    Během kultivace S. avermitilis v baňkách, 1- a 50-L fermentorech byl stanoven časový průběh produkce pachových látek, tj. geosminu a oxolonů, a avermektinů. Množství antibiotik a geosminů stoupalo s časem kultivace. Byla nalezena korelace mezi produkcí geosminu a produkcí avermektinů. Produkce oxolonů byla maximální po 3–5 dnech a pak poklesla pod měřitelnou úroveň. To lze připsat inhibici produkce oxolonů geosminem
    Permanent Link: http://hdl.handle.net/11104/0148189

     
     
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