Boron compounds as potential HIV-1 protease inhibitors

0030046 - ÚACH 2006 RIV JP eng C - Conference Paper (international conference)
Plešek, Jaromír - Grüner, Bohumír - Král, V. - Cígler, Petr - Kožíšek, Milan - Prejdová, Jana - Pokorná, Jana - Kräusslich, H. G. - Bodem, J. - Konvalinka, Jan
Boron compounds as potential HIV-1 protease inhibitors.
[Borové clastrové sloučeniny jako potenciální inhibitory HIV-1 proteásy.]
IMEBORON - XII. Tohoku: Graduate School of Science, 2005, s. 46.
[International Conference on Boron Chemistry /12./. Sendai (JP), 11.09.2005-15.09.2005]
R&D Projects: GA MŠMT(CZ) LC523
Institutional research plan: CEZ:AV0Z40320502
Keywords : boron cluster compounds
Subject RIV: CA - Inorganic Chemistry

Human immunodeficiency virus (HIV-1) is the etiological agent of the Acquired Immuno Deficiency Syndrome (AIDS). The HIV-1 replication cycle contains several virus-specific events that could be addressed by chemoterapeutic intervention. The cluster boron compounds represented thus a novel class of non-peptide and non-peptidomimetic inhibitors that differ substantially from the previously known organic series.

Borové clastrové sloučeniny jako potenciální inhibitory HIV-1 proteásy.
Permanent Link: http://hdl.handle.net/11104/0119823