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De novo design of alpha-amylase inhibitor: A small linear mimetic of macromolecular proteinaceous ligands

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    0025435 - ÚOCHB 2006 RIV US eng J - Journal Article
    Marešová, Lucie - Pavlík, Manfred - Horn, Martin - Mareš, Michael
    De novo design of alpha-amylase inhibitor: A small linear mimetic of macromolecular proteinaceous ligands.
    [De novo design inhibitoru alfa-amylas: Malé linearní mimetikum makromolekulárních proteinových ligandů.]
    Chemistry & Biology. Roč. 12, č. 12 (2005), 1349-1357. ISSN 1074-5521
    R&D Projects: GA ČR(CZ) GP203/02/P081; GA MŠMT(CZ) OC D16.001
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : amylase * peptide inhibitor * combinatorial chemistry
    Subject RIV: CE - Biochemistry
    Impact factor: 6.138, year: 2005

    First low molecular weight inhibitor of alpha-amylases based on acyclic peptidic scaffold was designed de novo through the use of combinatorial chemistry.

    První nízkomolekulární inhibitor alfa-amylas vyvinutý de novo byl připraven peptidovou kombinatorní chemií.
    Permanent Link: http://hdl.handle.net/11104/0115824

     
     
Number of the records: 1  

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