0637012 - ÚŽFG 2026 RIV DK eng J - Journal Article
Birjandi, A. A. - Lynham, S. - Matalová, Eva - Ghuman, M. - Sharpe, Paul
Regenerative Potential of PDL-Derived Small Extracellular Vesicles.
Journal of Periodontal Research. Roč. 60, č. 4 (2025), s. 392-394. ISSN 0022-3484. E-ISSN 1600-0765
R&D Projects: GA ČR(CZ) GA21-21409S
Institutional support: RVO:67985904
Keywords : periodontal treatment * stem cells
OECD category: Cell biology
Impact factor: 3.4, year: 2023 ; AIS: 0.782, rok: 2023
Method of publishing: Open access
Result website:
https://onlinelibrary.wiley.com/doi/10.1111/jre.13356DOI: https://doi.org/10.1111/jre.13356

The optimal healing outcome following periodontal treatment is complete periodontal regeneration which is very rarely achieved. Periodontal ligament (PDL) cells promote direct connective tissue attachment consistent with regenerative outcomes, whereas gingival connective tissue is not innately permissive. An alternative approach to promote regeneration is to alter the potential of gingival connective tissue to promote bone formation and connective tissue attachment. Multipotent mesenchymal stem cells have been isolated from gingival tissues and promote peri-implant bone regeneration
Permanent Link: https://hdl.handle.net/11104/0367971