Biological activities of new monohydroxylated brassinosteroid analogues with a carboxylic group in the side chain

0429538 - ÚEB 2015 RIV US eng J - Journal Article
Kvasnica, Miroslav - Oklešťková, Jana - Bazgier, Václav - Rárová, Lucie - Berka, K. - Strnad, Miroslav
Biological activities of new monohydroxylated brassinosteroid analogues with a carboxylic group in the side chain.
Steroids. Roč. 85, JUL 2014 (2014), s. 58-64. ISSN 0039-128X. E-ISSN 1878-5867
R&D Projects: GA MŠMT LK21306; GA MŠMT(CZ) LO1204
Grant - others:GA MŠk ED2.1.00/03.0058
Program: ED
Institutional support: RVO:61389030
Keywords : Anticancer activity * Brassinosteroids * Organic synthesis
Subject RIV: EF - Botanics
Impact factor: 2.639, year: 2014
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Thirteen monohydroxylated brassinosteroids analogues were synthesized and tested for their biological activity in plant and animal systems. The cytotoxic activity of the products was studied using human normal and cancer cell lines with 28-homocastasterone as positive control, their brassinolide type activity was established using the bean second-internode test with 24-epibrassinolide as standard.
Permanent Link: http://hdl.handle.net/11104/0234630