High-resolution time-lapse tomography of rat vertebrae during compressive loading: deformation response analysis

0429467 - ÚTAM 2015 RIV GB eng J - Journal Article
Fíla, Tomáš - Kytýř, Daniel - Zlámal, Petr - Kumpová, Ivana - Doktor, Tomáš - Koudelka_ml., Petr - Jiroušek, Ondřej
High-resolution time-lapse tomography of rat vertebrae during compressive loading: deformation response analysis.
Journal of Instrumentation. Roč. 9, May (2014), C05054. ISSN 1748-0221. E-ISSN 1748-0221.
[International workshop on radiation imaging detectors /15./. Paris, 23.06.2013-27.06.2013]
R&D Projects: GA ČR(CZ) GAP105/10/2305; GA MŠMT(CZ) LO1219
Institutional support: RVO:68378297
Keywords : image reconstruction in medical imaging * computerized tomography * computed radiography
Subject RIV: JJ - Other Materials
Impact factor: 1.399, year: 2014
http://iopscience.iop.org/1748-0221/9/05/C05054

This paper is focused on investigation of mechanical properties of rat vertebrae during compressive loading in the longitudinal direction of rat’s spine. High-resolution time-lapse micro-tomography was used as a tool to create models of the inner structure and deformed shape in pre-defined deformation steps. First, peripheral areas of vertebra specimen were embedded in polymethyl methacrylate to obtain proper boundary conditions of contact between specimen and loading plattens. Experimental loading device designed for application in X-ray setups was utilized to compress the vertebrae in several deformation steps. High-resolution micro-tomography scanning was carried out at each deformation step. Specimen was irradiated in tomography device equipped with microfocus X-ray tube with 5mm focal spot size and large area flat panel detector. Spatial resolution of reconstructed three-dimensional images was approximately 10mm. Digital volume correlation algorithm was utilized in order to assess displacements in the microstructure in every loading increment. Finite element model of vertebra was created from volumetric data reconstructed from tomography of the undeformed specimen. Simulated compressive test of the developed finite element model was performed in order to compare stiffness and displacements obtained by digital volume correlation and finite element simulation.
Permanent Link: http://hdl.handle.net/11104/0234578