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Alkaloids from Boophone haemanthoides (Amaryllidaceae)

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    0423125 - ÚEB 2014 RIV US eng J - Journal Article
    Nair, J. J. - Rárová, L. - Strnad, Miroslav - Bastida, J. - van Staden, J.
    Alkaloids from Boophone haemanthoides (Amaryllidaceae).
    Natural Product Communications. Roč. 8, č. 12 (2013), s. 1705-1710. ISSN 1934-578X. E-ISSN 1555-9475
    Institutional research plan: CEZ:AV0Z50380511
    Keywords : Alkaloid * Amaryllidaceae * Boophone haemanthoides
    Subject RIV: CE - Biochemistry
    Impact factor: 0.924, year: 2013
    http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord&UT=000328588200011

    In this study, the South African Amaryllid Boophone haemanthoides was examined for its phytochemical composition and cytotoxicity. In the process eight alkaloid structures, including the new compound distichaminol, were identified in bulb ethanolic extracts. Of the isolates, lycorine and distichamine exhibited strong activities against human acute lymphoblastic leukemia (CEM), breast adenocarcinoma (MCF7) and cervical adenocarcinoma (HeLa) cells with IC(50)s ranging from 1.8 to 9.2 mu M.
    Permanent Link: http://hdl.handle.net/11104/0229213

     
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