Acoustophoretic Focusing of Microparticles in Glass Microfluidic Device

0587020 - ÚIACH 2025 CZ eng A - Abstract
Novotný, Jakub - Březinová, L. - Týčová, Anna
Acoustophoretic Focusing of Microparticles in Glass Microfluidic Device.
MSB 2024. Final Program and Abstract Book. Brno: Ústav analytické chemie AV ČR, v. v. i., 2024 - (Lavická, J.; Přikryl, J.; Foret, F.). s. 162-162. ISBN 978-80-908154-1-4.
[MSB 2024. International Symposium on Microscale Separation and Bioanalysis /40./. 19.05.2024-22.05.2024, Brno]
Institutional support: RVO:68081715
Keywords : glass microfluidic device * cell lysis * microdroplet * microparticles * acoustic standing waves (ASWs) * surface-enhanced Raman spectroscopy (SERS)
OECD category: Analytical chemistry
https://www.msb2024.org/user_uploads/program/Program_and_Abstract_Book_final.pdf

Here, we present a glass microfluidic device for acoustophoretic focusing of particles suspended in liquid media. The glass device comprises a Y-shaped microchannel junction with two inlets and one outlet. A piezoceramic transducer, serving as the acoustic emitter, is securely attached to the glass surface near the microchannel to prevent any attenuation of the acoustic energy. The wavelength of the acoustic signal is set to double the width of the channel, generating a single-node ASW in the center of the channel. The dispersed particles migrate along the pressure gradient generated by the standing wave and accumulate at the node. We propose that the instant temporary accumulation of particles could benefit microscopic or spectral methods, such as surface-enhanced Raman spectroscopy (SERS), by concentrating them at a designated location in the channel, such as the focal point, thereby enhancing the output of these methods.
Permanent Link: https://hdl.handle.net/11104/0354339