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Sorbentless Dried Blood Spot Sampling for Automated DBS Analysis

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    0586986 - ÚIACH 2025 CZ eng A - Abstract
    Dvořák, Miloš - Profousová, Sylvie - Kubáň, Pavel
    Sorbentless Dried Blood Spot Sampling for Automated DBS Analysis.
    MSB 2024. Final Program and Abstract Book. Brno: Ústav analytické chemie AV ČR, v. v. i., 2024 - (Lavická, J.; Přikryl, J.; Foret, F.). s. 138-138. ISBN 978-80-908154-1-4.
    [MSB 2024. International Symposium on Microscale Separation and Bioanalysis /40./. 19.05.2024-22.05.2024, Brno]
    R&D Projects: GA ČR(CZ) GA23-05972S
    Institutional support: RVO:68081715
    Keywords : dried blood spot (DBS) * blood
    OECD category: Analytical chemistry
    https://www.msb2024.org/user_uploads/program/Program_and_Abstract_Book_final.pdf

    At present, the majority of dried blood spot (DBS) samples are collected on cellulose-based sampling cards. Recently, novel sampling materials and approaches were developed as attractive alternatives for blood
    collection. The rationale for their development was the detrimental effect of blood hematocrit on quantitative DBS analysis, the reduced elution recoveries of analytes, and the limited suitability for patient-centric blood collection of standard DBS cards. Moreover, porous sampling sorbents contain random production-borne species that can be released during sample preparation and contaminate the resulting eluate.
    Permanent Link: https://hdl.handle.net/11104/0354313

     
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