Oxidativní potenciál: Nový indikátor toxicity aerosolu

0585770 - ÚIACH 2025 RIV CZ cze J - Journal Article
Cigánková, Hana - Mikuška, Pavel
Oxidativní potenciál: Nový indikátor toxicity aerosolu.
[Oxidative Potential: A New Indicator of Aerosol Toxicity.]
Chemické listy. Roč. 118, č. 4 (2024), s. 195-201. ISSN 0009-2770. E-ISSN 1213-7103
R&D Projects: GA ČR(CZ) GA24-10051S
Institutional support: RVO:68081715
Keywords : aerosol * oxidative potential * acellular assays
OECD category: Analytical chemistry
Impact factor: 0.6, year: 2022

Atmospheric aerosol particles are considered to be a significant health risk worldwide. Although the exact mechanisms of aerosol toxicity are still not fully understood, several studies report that the generation of reactive oxygen species (ROS) is one of the main mechanisms responsible for chronic and acute health problems. For this reason, oxidative potential (OP) which is defined as the ability of an aerosol to generate ROS, has been proposed as a relevant parameter for assessing aerosol toxicity. This article describes different acellular in vitro methods to determine OP and the influence of chemical composition and aerosol size on OP.
Permanent Link: https://hdl.handle.net/11104/0353449