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Significance of muscle non-shivering thermogenesis in obesity-resistant mouse model
- 1.0583493 - FGÚ 2024 RIV US eng A - Abstract
Stanić, Sara - Janovská, Petra - Zouhar, Petr - Bardová, Kristina - Otáhal, Jakub - Vrbacký, Marek - Mráček, Tomáš - Adamcová, Kateřina - Čajka, Tomáš - Drahota, Zdeněk - Rustan, A. C. - Horáková, Olga - Houštěk, Josef - Rossmeisl, Martin - Kopecký, Jan
Significance of muscle non-shivering thermogenesis in obesity-resistant mouse model.
European Journal of Clinical Investigation. Wiley. Roč. 53, Suppl.1 (2023), č. článku 57ASM-100. ISSN 0014-2972. E-ISSN 1365-2362.
[ANNUAL SCIENTIFIC MEETING /57./. 07.06.2023-09.06.2023, Praha]
R&D Projects: GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:67985823
Keywords : obesity * nonshivering thermogenesis * skeletal muscle
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Result website:
https://onlinelibrary.wiley.com/doi/10.1111/eci.13992DOI: https://doi.org/10.1111/eci.13992
Impaired adrenergic NST in BAT of A/J mice could be compensated by NST in skeletal muscle. Muscle NST seems to be inducible by cold and it may provide not only protection from cold, but also obesity resistance, more effectively than BAT. Heart may play an important strain- specific role in regulation of muscular NST.
Permanent Link: https://hdl.handle.net/11104/0351457
Number of the records: 1