Sensitivity of endogenous autofluorescence in HeLa cells to the application of external magnetic fields

0573430 - FZÚ 2024 RIV US eng J - Journal Article
Uzhytchak, Mariia - Smolková, Barbora - Frtús, Adam - Stupakov, Alexandr - Lunova, Mariia - Scollo, Federica - Hof, Martin - Jurkiewicz, Piotr - Sullivan, G.J. - Dejneka, Alexandr - Lunov, Oleg
Sensitivity of endogenous autofluorescence in HeLa cells to the application of external magnetic fields.
Scientific Reports. Roč. 13, July (2023), č. článku 10818. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) EF16_019/0000760
Grant - others:OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institutional support: RVO:68378271 ; RVO:61388955
Keywords : fluorescence * autofluorescence * quantitative confocal microscopy * magnetic field * electromagnetic radiation
OECD category: Biophysics; Physical chemistry (UFCH-W)
Impact factor: 4.6, year: 2022
Method of publishing: Open access

Dramatically increased levels of electromagnetic radiation in the environment have raised concerns over the potential health hazards of electromagnetic fields. Despite decades of intensive research, the molecular mechanisms procuring cellular responses remain largely unknown. Therefore, a search for potential direct cellular effects of magnetic fields represents a cornerstone that may propose an explanation for potential health hazards associated with magnetic fields. It has been proposed that autofluorescence of HeLa cells is magnetic field sensitive, relying on single-cell imaging kinetic measurements. Here, we investigate the magnetic field sensitivity of an endogenous autofluorescence in HeLa cells. Magnetic field sensitivity of an endogenous autofluorescence was not observed in HeLa cells. We present a number of arguments indicating why this is the case in the analysis of magnetic field effects based on the imaging of cellular autofluorescence decay.
Permanent Link: https://hdl.handle.net/11104/0343873