Development of Efficient Coupling of Capillary Electrophoresis and Surface-Enhanced Raman Spectrometry (CE-SERS)

0573262 - ÚIACH 2024 DE eng A - Abstract
Týčová, Anna - Novotný, Jakub - Přikryl, Jan - Belder, D. - Foret, František
Development of Efficient Coupling of Capillary Electrophoresis and Surface-Enhanced Raman Spectrometry (CE-SERS).
HPLC 2023. Final Program. Frankfurt am Main: Gesellschaft Deutscher Chemiker e.V., 2023 - (Lämmerhofer, M.; Schmitz, O.), č. článku SOR14.
[International Symposium on High-Performance Liquid Phase Separations and Related Techniques (HPLC 2023) /51./. 18.06.2023-22.06.2023, Duesseldorf]
Institutional support: RVO:68081715
Keywords : CE-SERS * nanoparticles * SERS signal
OECD category: Analytical chemistry

Efficient coupling of capillary electrophoresis to surface-enhanced Raman spectrometry (CE-SERS) has a capacity to combine high separation power with the universal and ultrasensitive detection. As the signal originates from molecular vibrations, SERS can clearly identify an analyte and provide complementary data to predominantly used mass spectrometry. The principle of SERS detection requires the presence of nanostructures and their close interaction with the analytes, both of which challenge the superior separation efficiency of electrophoresis. This substantial prerequisite causes that despite the high attractiveness of CE-SERS coupling, only few achievements have been in this field reported so far.
Permanent Link: https://hdl.handle.net/11104/0343732