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A method for functionalization of an aromatic amino acid or a nucleobase
- 1.0573173 - ÚOCHB 2024 RIV eng P - Patent Document
Matoušek, V. - Beier, Petr - Novák, Petr
A method for functionalization of an aromatic amino acid or a nucleobase.
2023. Owner: CF Plus Chemicals, s. r. o. - Ústav organické chemie a biochemie AV ČR, v. v. i. - Mikrobiologický ústav AV ČR, v. v. i. Date of the patent acceptance: 19.04.2023. Patent Number: EP3966203. Territorial Protection: evropský patent podle Evropské patentové úmluvy .
Institutional support: RVO:61388963 ; RVO:61388971
Keywords : fluoroalkylation * hypervalent iodine compounds * bioconjugation
OECD category: Organic chemistry
https://worldwide.espacenet.com/patent/search/family/066429258/publication/EP3966203B1?q=EP%203966203B1
The present invention provides a method for functionalization of an aromatic amino acid or a nucleobase with a fluoroalkyl-containing moiety RF, wherein the aromatic amino acid is reacted in the presence of at least one reductant with at least one hypervalent iodine fluoroalkyl reagent carrying said floroalkyl-containing moiety RF. The invention further provides novel hypervalent iodine fluoroalkyl reagents.
Permanent Link: https://hdl.handle.net/11104/0343630
Number of the records: 1