0572088 - MBÚ 2024 RIV CH eng J - Journal Article
Sushytskyi, Leonid - Synytsya, A. - Čopíková, J. - Lukáč, Pavol - Rajsiglová, Lenka - Tenti, Paolo - Vannucci, Luca
Perspectives in the Application of High, Medium, and Low Molecular Weight Oat beta-D-Glucans in Dietary Nutrition and Food Technology-A Short Overview.
Foods. Roč. 12, č. 6 (2023), č. článku 1121. ISSN 2304-8158. E-ISSN 2304-8158
R&D Projects: GA MŠMT LX22NPO5102
Institutional support: RVO:61388971
Keywords : cereal beta-D-glucans * oats * molecular weight * glycaemia * immunity * microbiome * cancer
OECD category: Oncology
Impact factor: 4.7, year: 2023 ; AIS: 0.676, rok: 2023
Method of publishing: Open access
Result website:
https://www.mdpi.com/2304-8158/12/6/1121DOI: https://doi.org/10.3390/foods12061121

For centuries human civilization has cultivated oats, and now they are consumed in various forms of food, from instant breakfasts to beverages. They are a nutrient-rich food containing linear mixed-linkage (1> 3) (1> 4)-beta-D-glucans, which are relatively well soluble in water and responsible for various biological effects: the regulation of the blood cholesterol level, as well as being anti-inflammatory, prebiotic, antioxidant, and tumor-preventing. Numerous studies, especially in the last two decades, highlight the differences in the biological properties of the oat beta-D-glucan fractions of low, medium, and high molecular weight. These fractions differ in their features due to variations in bioavailability related to the rheological properties of these polysaccharides, and their association with food matrices, purity, and mode of preparation or modification. There is strong evidence that, under different conditions, the molecular weight may determine the potency of oat-extracted beta-D-glucans. In this review, we intend to give a concise overview of the properties and studies of the biological activities of oat beta-D-glucan preparations depending on their molecular weight and how they represent a prospective ingredient of functional food with the potential to prevent or modulate various pathological conditions.
Permanent Link: https://hdl.handle.net/11104/0342915