Feature-overlapper: The tool for DNA analysis overlap

0571535 - BFÚ 2024 RIV NL eng J - Journal Article
Havlík, J. - Brázda, Václav - Stanek, K. - Ježek, M. - Šťastný, J.
Feature-overlapper: The tool for DNA analysis overlap.
SOFTWARE IMPACTS. Roč. 16, MAY 2023 (2023), č. článku 100498. ISSN 2665-9638
Institutional support: RVO:68081707
Keywords : dna * R-loop * G-quadruplex * Annotation
OECD category: Cell biology
Impact factor: 2.1, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S2665963823000350?via%3Dihub

This contribution puts focus on a command line tool, which enables detection and analysis of overlapping regions between G-quadruplexes, R-loops and genome annotations for selected genomes. G-quadruplexes and R-loops are structures with high Guanine density, which is an important creation factor for both structures. Common regions (overlap) between both structures can provide us with better possibility to create precise model to detect R-loops and valuable insights when inspecting genome annotations with high R-loop density. The tool was used for multiple research projects and is under constant development bringing new features to the world of bioinformatics.
Permanent Link: https://hdl.handle.net/11104/0349900