Arrangements of DNA purine bases on pyrolytic graphite electrode surface. Electrochemical characterization and atomic force microscopy imaging

0571530 - BFÚ 2024 RIV GB eng J - Journal Article
Hasoň, Stanislav - Ostatná, Veronika - Fojta, Miroslav - Fojt, Lukáš
Arrangements of DNA purine bases on pyrolytic graphite electrode surface. Electrochemical characterization and atomic force microscopy imaging.
Electrochimica acta. Roč. 441, FEB 10 2023 (2023), č. článku 141772. ISSN 0013-4686. E-ISSN 1873-3859
R&D Projects: GA ČR(CZ) GA20-03187S
Institutional support: RVO:68081707
Keywords : Adenine and guanine adsorption * Guanine stacking on pyrolytic graphite * Voltammetric and capacitance measurements * Atomic force microscopy * Experiment and theoretical calculation
OECD category: Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)
Impact factor: 6.6, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0013468622019284?via%3Dihub

In this work we experimentally show the formation of a planarly-arranged guanine multilayer on a pyrolytic graphite surface, which was predicted by theoretical calculations at the ideal graphene surface. In the case of adenine, a multilayered architecture like that of guanine was not confirmed. Changes in the purine bases' arrangement on charged surface in dependence on their concentration is studied using electrooxidation peaks of guanine and adenine, together with time changes in capacitance of electric double layer. Existence of predicted guanine multilayers is supported by electrochemical findings and confirmed by atomic force microscopy. Moreover, our data suggest a link between an additional guanine electrooxidation peak and supramolecular guanine assembly formation.
Permanent Link: https://hdl.handle.net/11104/0346069