Nucleic acids movement and its relation to genome dynamics of repetitive DNA Is cellular and intercellular movement of DNA and RNA molecules related to the evolutionary dynamic genome components?

0569371 - BFÚ 2023 RIV GB eng J - Journal Article
Kejnovský, Eduard - Jedlička, Pavel
Nucleic acids movement and its relation to genome dynamics of repetitive DNA Is cellular and intercellular movement of DNA and RNA molecules related to the evolutionary dynamic genome components?
BioEssays. Roč. 44, č. 4 (2022), č. článku e2100242. ISSN 0265-9247. E-ISSN 1521-1878
R&D Projects: GA ČR(CZ) GA18-00258S; GA ČR(CZ) GA21-00580S
Institutional support: RVO:68081707
Keywords : dna * genome dynamics * horizontal gene transfer * migration * movement * small RNA * transposable elements
OECD category: Biochemistry and molecular biology
Impact factor: 4, year: 2022
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/10.1002/bies.202100242

There is growing evidence of evolutionary genome plasticity. The evolution of repetitive DNA elements, the major components of most eukaryotic genomes, involves the amplification of various classes of mobile genetic elements, the expansion of satellite DNA, the transfer of fragments or entire organellar genomes and may have connections with viruses. In addition to various repetitive DNA elements, a plethora of large and small RNAs migrate within and between cells during individual development as well as during evolution and contribute to changes of genome structure and function. Such migration of DNA and RNA molecules often results in horizontal gene transfer, thus shaping the whole genomic network of interconnected species. Here, we propose that a high evolutionary dynamism of repetitive genome components is often related to the migration/movement of DNA or RNA molecules. We speculate that the cytoplasm is probably an ideal compartment for such evolutionary experiments.
Permanent Link: https://hdl.handle.net/11104/0340689