Gradient magnetic field accelerates division of E.coli Nissle 1917

0568521 - FZÚ 2024 RIV CH eng J - Journal Article
Gorobets, S. - Gorobets, O. - Sharai, I. - Polyakova, Tetyana - Zablotskii, Vitalii
Gradient magnetic field accelerates division of E.coli Nissle 1917.
Cells. Roč. 12, č. 2 (2023), č. článku 315. E-ISSN 2073-4409
R&D Projects: GA MŠMT(CZ) EF16_019/0000760
Grant - others:OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institutional support: RVO:68378271
Keywords : bacterial division * magnetic field * biomagnetic effects * mitosis * intracellular forces
OECD category: Biophysics
Impact factor: 6, year: 2022
Method of publishing: Open access

Cell-cycle progression is regulated by numerous intricate endogenous mechanisms, among which intracellular forces and protein motors are central players. Although it seems unlikely that it is possible to speed up this molecular machinery by applying tiny external forces to the cell, we show that magnetic forcing of magnetosensitive bacteria reduces the duration of the mitotic phase. In such bacteria, the coupling of the cell cycle to the splitting of chains of biogenic magnetic nanoparticles (BMNs) provides a biological realization of such forcing. Using a static gradient magnetic field of a special spatial configuration, in probiotic bacteria E. coli Nissle 1917, we shortened the duration of the mitotic phase and thereby accelerated cell division.
Permanent Link: https://hdl.handle.net/11104/0342085