Synthesis, Characterization, and Physicochemical Studies Of Orientation-Controlled Multi-Arm PEG Zn(II)/Mg(II) (Aza)Phthalocyanines

0568200 - ÚFCH JH 2023 RIV DE eng J - Journal Article
Husain, A. - Ganesan, A. - Salah, L. - Kubát, Pavel - Ghazal, B. - Makhseed, S.
Synthesis, Characterization, and Physicochemical Studies Of Orientation-Controlled Multi-Arm PEG Zn(II)/Mg(II) (Aza)Phthalocyanines.
ChemPlusChem. Roč. 87, č. 11 (2022), č. článku e202200275. ISSN 2192-6506. E-ISSN 2192-6506
Institutional support: RVO:61388955
Keywords : amphiphiles * fluorescence quantum yields * macrocycles * phthalocyanines * polyethylene glycol * singlet oxygen generation
OECD category: Physical chemistry
Impact factor: 3.4, year: 2022
Method of publishing: Limited access

Tuning the amphiphilicity of (aza)phthalocyanine hydrophobic cores by introducing multiple polyethylene glycol (PEG) moieties with controlled orientations of their (non)peripheral positions is an innovative approach to fabricating water-soluble macrocyclic materials. Although many water-soluble PEGylated macrocycles have been produced in this way, the ability to generate substances with PEG tails oriented outward from the macrocyclic plane in order to obtain non-aggregated, water soluble forms remains a challenge. In this study, we resolved this issue by developing a methods for the synthesis of four new dual directional PEG containing Zn(II)/Mg(II) amphiphiles (ZnPc-PEG, MgPc-PEG, ZnAzaPc-PEG and MgAzaPc-PEG). In addition, the non-aggregating behaviour, and photophysical and photochemical properties of these PEG-complexes were elucidated.
Permanent Link: https://hdl.handle.net/11104/0339533