Composition-switchable liquid crystalline nanostructures as green formulations of curcumin and fish oil

0563424 - FZÚ 2023 RIV US eng J - Journal Article
Rakotoarisoa, M. - Angelov, Borislav - Espinoza Herrera, Shirly J. - Khakurel, Krishna - Bizien, T. - Drechsler, M. - Angelova, A.
Composition-switchable liquid crystalline nanostructures as green formulations of curcumin and fish oil.
ACS Sustainable Chemistry & Engineering. Roč. 9, č. 44 (2021), s. 14821-14835. ISSN 2168-0485. E-ISSN 2168-0485
R&D Projects: GA MŠMT EF15_003/0000447; GA MŠMT EF16_019/0000789
Grant - others:OP VVV - ELIBIO(XE) CZ.02.1.01/0.0/0.0/15_003/0000447; OP VVV - ADONIS(XE) CZ.02.1.01/0.0/0.0/16_019/0000789; AV ČR(CZ) MSM100101901
Program: Program na podporu mezinárodní spolupráce začínajících výzkumných pracovníků
Institutional support: RVO:68378271
Keywords : phytochemical antioxidant * nanocurcumin * lipid-based lyotropic liquid crystalline phases * sustainable nanoformulations * safe biodegradable
OECD category: Biochemistry and molecular biology
Impact factor: 9.224, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acssuschemeng.1c04706

Green compositions and processes for fabrication of dual- and multiloaded nanocarriers with an antioxidant functionality and neuroprotective, cardioprotective, antiviral, and antiproliferative activities are of broad interest for innovations in pharmaceutics and nutraceutics. Coencapsulation of curcumin (studied as a key multipurpose phytochemical antioxidant) with ω-3 polyunsaturated fatty acids (PUFAs) (studied as active ingredients of natural fish oil) may increase the oxidative stability of self-assembled formulations aiming at the development of “food drugs” and prevention of disease progression in various pathological states.
Permanent Link: https://hdl.handle.net/11104/0335392