A method for single particle tracking through a multimode fiber

0562784 - ÚPT 2023 RIV US eng J - Journal Article
Cifuentes, Angel S. - Traegaardh, Johanna
A method for single particle tracking through a multimode fiber.
Optics Express. Roč. 30, č. 20 (2022), s. 36055-36064. ISSN 1094-4087
R&D Projects: GA ČR(CZ) GA22-27726S; GA MŠMT EF15_003/0000476
EU Projects: European Commission(XE) 829116 - Super-Pixels
Institutional support: RVO:68081731
Keywords : multimode optical fibers * fibre endoscopy
OECD category: Optics (including laser optics and quantum optics)
Impact factor: 3.8, year: 2022
Method of publishing: Open access
https://opg.optica.org/oe/fulltext.cfm?uri=oe-30-20-36055&id=503272

Multimode optical fiber (MMF) endoscopes have recently gained widespread attention as a novel tool for imaging deep within tissue using light microscopy. We here present a method for particle tracking through the MMF, which overcomes the lack of a fast enough wide-field fluorescence imaging modality for this type of endoscope, namely a discrete implementation of orbital particle tracking. We achieve biologically relevant tracking speeds (up to 1.2 µm/s) despite using a slow SLM for the wavefront shaping. We demonstrate a tracking accuracy of λ/50 for a 0.3 NA fiber and show tracking of a pinhole moving to mimic Brownian motion with diffusion rates of up to 0.3 µm2/s.
Permanent Link: https://hdl.handle.net/11104/0334982