Multifunctional surface functionalized magnetic iron oxide nanoparticles for biomedical applications: A review

0562754 - ÚŽFG 2023 RIV NL eng J - Journal Article
Gambhir, R. P. - Rohiwal, Sonali Suresh - Tiwari, A. P.
Multifunctional surface functionalized magnetic iron oxide nanoparticles for biomedical applications: A review.
Applied Surface Science Advances. Roč. 11, OCT 2022 (2022), č. článku 100303. ISSN 2666-5239
Institutional support: RVO:67985904
Keywords : Magnetic * Nanoparticles * Multifunctional * Surface functionalization * Biomedical applications * covid19
OECD category: Biomaterials (as related to medical implants, devices, sensors)
Impact factor: 6.2, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S2666523922000939?via%3Dihub

Magnetic iron oxide nanoparticle-based multifunctional platforms have been explored extensively in biomedical applications. Modifications and integrations of IONPs with different entities viz. organic polymer, doping with inorganic materials, loading with drug, fluorescent dye, or antibodies make them appropriate for their appli-cation in broad spectrum of biomedical fields. This review presents and summarizes the fabrication strategies of multifunctional magnetic nanoparticles based on the modification and surface functionalization of MNP. Multifunctional IONPs based recent advances covering a wide array of applications like biosensing and pathogen detection, magnetic resonance imaging (MRI) and biomarker tracking, magnetofection and gene therapy, hy-perthermia and chemotherapy, drug delivery and targeted cell killing, bioimaging and therapeutics, stem cell detection and therapy, tissue engineering and organ transplant, nano-vaccines and immune system activation, microbe targeting and destruction, and COVID19 management are also covered.
Permanent Link: https://hdl.handle.net/11104/0335548