0562120 - ÚIACH 2023 RIV CZ eng C - Conference Paper (international conference)
Cigánková, Hana - Mikuška, Pavel - Hegrová, J.
Oxidative Potential of PM1 and PM2.5 Urban Aerosol and Associated Elements in Three Simulated Lung Fluids.
Sborník 21. výroční konference České aerosolové společnosti. Prague: Czech Aerosol Society, 2022 - (Lhotka, R.), s. 55-56. ISBN 978-80-908653-0-3.
[výroční konference České aerosolové společnosti /21./. Kutná hora (CZ), 03.10.2022-04.10.2022]
R&D Projects: GA ČR(CZ) GA20-02203S
Institutional support: RVO:68081715
Keywords : aerosol * oxidative potential * elements
OECD category: Analytical chemistry

Mass concentration of particulate matter (PM) has been used in several epidemiologic studies as an indicatior conenecting PM concentrations with human health effects (Ostro, 1993). However, mass concentration of PM doesn´t consider the different compositions and toxicological effects of its components. Majority of PM mass constitutes low-toxicity components, while minority of trace components may have high toxicological activity (Tonne, 2012). Oxidative potential (OP), defined as the ability of PM to induce oxidative stress, is in recent years recognized as one of the main biological mechanisms considered to be contributing to negative impacts from air pollution exposure. Oxidative stress is caused through the capability of PM to generate reactive oxygen species (ROS) within the lung, which leads to pro-inflammatory responses that can ultimately results in cell apoptosis (Borlaza, 2021).
Permanent Link: https://hdl.handle.net/11104/0334535