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Tuning of magnetic hyperthermia response in the systems containing magnetosomes

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    0562005 - BC 2023 RIV CH eng J - Journal Article
    Molčan, M. - Skumiel, A. - Timko, M. - Šafařík, Ivo - Zolochevská, K. - Kopčanský, P.
    Tuning of magnetic hyperthermia response in the systems containing magnetosomes.
    Molecules. Roč. 27, č. 17 (2022), č. článku 5605. E-ISSN 1420-3049
    Institutional support: RVO:60077344
    Keywords : alternating magnetic field * rotating magnetic field * magnetic nanoparticles * magnetic hyperthermia * heat evolution
    OECD category: Particles and field physics
    Impact factor: 4.6, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/1420-3049/27/17/5605

    A number of materials are studied in the field of magnetic hyperthermia. In general, the most promising ones appear to be iron oxide particle nanosystems. This is also indicated in some clinical trial studies where iron-based oxides were used. On the other hand, the type of material itself provides a number of variations on how to tune hyperthermia indicators. In this paper, magnetite nanoparticles in various forms were analyzed. The nanoparticles differed in the core size as well as in the form of their arrangement. The arrangement was determined by the nature of the surfactant. The individual particles were covered chemically by dextran, in the case of chain-like particles, they were encapsulated naturally in a lipid bilayer. It was shown that in the case of chain-like nanoparticles, except for relaxation, a contribution from magnetic hysteresis to the heating process also appears. The influence of the chosen methodology of magnetic field generation was also analyzed. In addition, the influence of the chosen methodology of magnetic field generation was analyzed. The application of a rotating magnetic field was shown to be more efficient in generating heat than the application of an alternating magnetic field. However, the degree of efficiency depended on the arrangement of the magnetite nanoparticles. The difference in the efficiency of the rotating magnetic field versus the alternating magnetic field was much more pronounced for individual nanoparticles (in the form of a magnetic fluid) than for systems containing chain nanoparticles (magnetosomes and a mix of magnetic fluid with magnetosomes in a ratio 1:1).
    Permanent Link: https://hdl.handle.net/11104/0336765

     
     
Number of the records: 1  

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