Capillary Electrophoresis-Mass Spectrometry : Methods and Protocols

0559742 - ÚIACH 2023 RIV US eng M - Monography Chapter
Lavická, Jana - Foret, František
Microfabricated Liquid Junction Capillary Electrophoresis–Mass Spectrometry Interface.
Capillary Electrophoresis-Mass Spectrometry : Methods and Protocols. New York: Humana New York, 2022 - (Neusüß, C.; Jooß, K.), s. 61-68. Methods in Molecular Biology, volume 2531. ISBN 978-1-0716-2492-0
R&D Projects: GA ČR(CZ) GA22-00236S
Grant - others:AV ČR(CZ) MTA-19-06
Program: Bilaterální spolupráce
Institutional support: RVO:68081715
Keywords : capillary electrophoresis * mass spectrometry * CE-MS interface * liquid junction
OECD category: Analytical chemistry
https://link.springer.com/book/9781071624920

Coupling of capillary electrophoresis (CE) with mass spectrometry (MS) represents a powerful combination for performing rapid, efficient, and sensitive analysis of a variety of compounds. Here we describe a construction, operation, and application of a microfabricated liquid junction CE-MS interface. The interface is designed as a microfabricated unit with an integrated liquid junction and electrospray tip made from polyimide, which is positioned in a plastic connection block securing the separation CE capillary and attachable to the CE instrument. The application was demonstrated by CE-MS analysis of dextran oligomers labeled by (2-aminoethyl)trimethylammonium (AETMA) salt.
Permanent Link: https://hdl.handle.net/11104/0332946