Porous polydimethylsiloxane composite filled with graphene oxide and gold nanoparticles produced by laser ablation in liquids

0557581 - ÚJF 2023 RIV GB eng J - Journal Article
Cutroneo, Mariapompea - Havránek, Vladimír - Torrisi, L. - Silipigni, L. - Kováčik, L. - Malinský, Petr - Slepička, P. - Fajstavr, D. - Janoušková, O. - Zbořilová, D. - Macková, Anna
Porous polydimethylsiloxane composite filled with graphene oxide and gold nanoparticles produced by laser ablation in liquids.
Vacuum. Roč. 199, MAY (2022), č. článku 110951. ISSN 0042-207X. E-ISSN 1879-2715
R&D Projects: GA MŠMT EF16_013/0001812; GA ČR GA19-02482S
Research Infrastructure: CANAM II - 90056; NanoEnviCz II - 90124
Institutional support: RVO:61389005
Keywords : nanoparticles * graphene oxide * polydimethylsiloxane * laser ablation in liquid * biomaterial
OECD category: Coating and films
Impact factor: 4, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.vacuum.2022.110951

The design of new materials with improved mechanical and biological properties is a major interest in biomedical applications. This paper presents the synthesis of macro-porous polydimethylsiloxane (PDMS) sponge composites as potential materials for tissue engineering. PDMS sponge with pores size ranging between 50 and 900 mu m was produced using the sugar templating process. The sponges were decorated with graphene oxide and gold nanoparticles created by the laser ablation in liquid and then they were morphologically, mechanically and biologically characterized. The optical properties of all the solutions containing nanoparticles were studied with the UV-ViS spectroscopy. The biological behaviour and performance of native PDMS, PDMS decorated with graphene oxide, and with graphene oxide and gold nanoparticles were compared. Results show that the composites and equally as important the adopted processing are both biocompatible. The quality of filler dispersion in the porous composites was observed by scanning electron (SEM) and atomic force (AFM) microscopies. The biocompatibility of the composites and of the preparation procedure was confirmed by monitoring the cytotoxicity of the composites for different types of cell cultures.
Permanent Link: http://hdl.handle.net/11104/0331540