Eukaryotic cellular intricacies shape mitochondrial proteomic complexity

0557222 - BC 2023 RIV GB eng J - Journal Article
Hammond, Michael John - Dorrell, R.G. - Speijer, D. - Lukeš, Julius
Eukaryotic cellular intricacies shape mitochondrial proteomic complexity.
BioEssays. Roč. 44, č. 5 (2022), č. článku e2100258. ISSN 0265-9247. E-ISSN 1521-1878
R&D Projects: GA MŠMT(CZ) LL1601; GA ČR(CZ) GA20-07186S; GA ČR(CZ) GA21-09283S; GA MŠMT(CZ) EF16_019/0000759
Institutional support: RVO:60077344
Keywords : cyclic electron flow * protein import * subcellular-localization * evolution * arabidopsis * genome * diversification * photosynthesis * chloroplasts * biogenesis * mass spectrometry * mitoproteome * multicellularity * parasite * photosynthesis * plastid * protist
OECD category: Genetics and heredity (medical genetics to be 3)
Impact factor: 4, year: 2022
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/10.1002/bies.202100258

Mitochondria have been fundamental to the eco-physiological success of eukaryotes since the last eukaryotic common ancestor (LECA). They contribute essential functions to eukaryotic cells, above and beyond classical respiration. Mitochondria interact with, and complement, metabolic pathways occurring in other organelles, notably diversifying the chloroplast metabolism of photosynthetic organisms. Here, we integrate existing literature to investigate how mitochondrial metabolism varies across the landscape of eukaryotic evolution. We illustrate the mitochondrial remodelling and proteomic changes undergone in conjunction with major evolutionary transitions. We explore how the mitochondrial complexity of the LECA has been remodelled in specific groups to support subsequent evolutionary transitions, such as the acquisition of chloroplasts in photosynthetic species and the emergence of multicellularity. We highlight the versatile and crucial roles played by mitochondria during eukaryotic evolution, extending from its huge contribution to the development of the LECA itself to the dynamic evolution of individual eukaryote groups, reflecting both their current ecologies and evolutionary histories.
Permanent Link: https://hdl.handle.net/11104/0339076