Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen Cladonia metacorallifera

0556156 - MBÚ 2023 RIV CH eng J - Journal Article
Sepúlveda, B. - Cornejo, A. - Bárcenas-Pérez, Daniela - Cheel Horna, José - Areche, C.
Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen Cladonia metacorallifera.
Separations. Roč. 9, č. 2 (2022), č. článku 41. E-ISSN 2297-8739
R&D Projects: GA TA ČR(CZ) TN01000048; GA MŠMT(CZ) LO1416
Institutional support: RVO:61388971
Keywords : Antarctica * Cladonia * depsides * depsidones * Fumarprotocetraric acid * lichens * uhplc * esi * ms
OECD category: Microbiology
Impact factor: 2.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2297-8739/9/2/41

Lichens are symbiotic organisms between algae and fungi, which are makers of secondary compounds named as lichen substances. Hyphenated techniques have significantly helped natural product chemistry, especially UHPLC/ESI/MS/MS in the identification, separation, and tentative characterization of secondary metabolites from natural sources. Twenty-five compounds were detected from the Antarctic lichen Cladonia metacorallifera for the first time using UHPLC-PDA/ESI/Orbitrap/MS/MS. Compounds 5 and 7 are reported as new compounds, based on their MS/MS fragmentation routes, and considered as fumarprotocetraric acid derivatives. Besides, ten known phenolic identified as orsellinic acid, ethyl 4-carboxyorsellinate, psoromic acid isomer, succinprotocetraric acid, siphulellic acid, connorstictic acid, cryptostictic acid, lecanoric acid, lobaric acid and gyrophoric acid are noticed for the first time in the Cladonia genus.
Permanent Link: http://hdl.handle.net/11104/0331320