Field-effect transistor with a plasmonic fiber optic gate electrode as a multivariable biosensor device

0555942 - FZÚ 2023 RIV US eng J - Journal Article
Hasler, R. - Reiner-Rozman, C. - Fossati, S. - Aspermair, P. - Dostálek, Jakub - Lee, S. - Ibanez, M. - Bintinger, J. - Knoll, W.
Field-effect transistor with a plasmonic fiber optic gate electrode as a multivariable biosensor device.
ACS Sensors. Roč. 7, č. 2 (2022), s. 504-512. ISSN 2379-3694. E-ISSN 2379-3694
Institutional support: RVO:68378271
Keywords : electrolyte-gated field-effect transistor (EG-FET) * surface plasmon resonance (SPR) * layer-by-layer (LBL) assemblies * surface investigation * multivariant sensing * fiber optics * sensor geometry
OECD category: Biochemical research methods
Impact factor: 8.9, year: 2022
Method of publishing: Open access

A novel multivariable system, combining a transistor with fiber optic-based surface plasmon resonance spectroscopy with the gate electrode simultaneously acting as the fiber optic sensor surface, is reported. The dual-mode sensor allows for discrimination of mass and charge contributions for binding assays on the same sensor surface. Furthermore, we optimize the sensor geometry by investigating the influence of the fiber area to transistor channel area ratio and distance. We show that larger fiber optic tip diameters are favorable for electronic and optical signals and demonstrate the reversibility of plasmon resonance wavelength shifts after electric field application.
Permanent Link: http://hdl.handle.net/11104/0330768