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Role of miR-653 and miR-29c in downregulation of CYP1A2 expression in hepatocellular carcinoma
- 1.0555407 - BFÚ 2022 RIV PL eng J - Journal Article
Krkoška, Martin - Nekvindová, J. - Nevědělová, Kateřina - Zubanova, V. - Radová, L. - Vondráček, Jan - Herudková, Jarmila - Slabý, O. - Kiss, I. - Bohovicova, L. - Fabián, P. - Tylichová, Zuzana - Kala, Z. - Kysela, P. - Ostrizkova, L. - Palička, V. - Vaculová, Alena
Role of miR-653 and miR-29c in downregulation of CYP1A2 expression in hepatocellular carcinoma.
Pharmacological Reports. Roč. 74, č. 1 (2022), s. 148-158. ISSN 1734-1140. E-ISSN 2299-5684
R&D Projects: GA MZd(CZ) NV17-28231A
Institutional support: RVO:68081707
Keywords : aryl-hydrocarbon receptor * tumor-suppressor * human liver * posttranscriptional regulation * cell-line * cytochrome-p450
OECD category: Pharmacology and pharmacy
Impact factor: 4.4, year: 2022 ; AIS: 0.581, rok: 2022
Method of publishing: Limited access
Result website:
https://link.springer.com/article/10.1007/s43440-021-00338-9DOI: https://doi.org/10.1007/s43440-021-00338-9
Background Hepatocellular carcinoma (HCC) is a major contributor to the worldwide cancer burden. Recent studies on HCC have demonstrated dramatic alterations in expression of several cytochrome P450 (CYP) family members that play a crucial role in biotransformation of many drugs and other xenobiotics, however, the mechanisms responsible for their deregulation remain unclear.
Permanent Link: http://hdl.handle.net/11104/0329927
Number of the records: 1