Characterization and applications of a trioctyl(3/4-vinylbenzyl)phosphonium stationary phase for use in capillary liquid chromatography

0555280 - ÚIACH 2023 RIV NL eng J - Journal Article
Moravcová, Dana - Planeta, Josef - Karásek, Pavel - King, A. W. T. - Wiedmer, S. K.
Characterization and applications of a trioctyl(3/4-vinylbenzyl)phosphonium stationary phase for use in capillary liquid chromatography.
Journal of Chromatography A. Roč. 1666, MAR (2022), č. článku 462866. ISSN 0021-9673. E-ISSN 1873-3778
R&D Projects: GA ČR(CZ) GA19-00742S
Institutional support: RVO:68081715
Keywords : confined ionic liquid * monolithic column * separation * extraction
OECD category: Analytical chemistry
Impact factor: 4.1, year: 2022
Method of publishing: Limited access

The morphology, composition, and selectivity of a silica-based monolithic stationary phase, grafted by a layer of trioctyl(3/4-vinylbenzyl)phosphonium chloride ([P-888vBn ]Cl), is presented. The results of elemental analysis confirmed that the prepared stationary phase contains 38.8 at.% of silicon, 60.2 at.% of carbon, and 1.0 at.% of phosphorus. Capillary columns (150 x 0.1 mm) for liquid chromatography were evaluated using alkylbenzenes, monosubstituted benzenes, polyaromatic compounds, substituted benzene regioisomers, and aromatic carboxylic and amino acids. The prepared ionic liquid (IL)-based stationary phase exhibits hydrophobic, hydrophilic, and electrostatic interactions, as confirmed by experiments on the evaluation of the effect of the mobile phase composition (content of acetonitrile and ammonium formate) on the isocratic chromatographic separation. Thus, the IL-based capillary column demonstrates a unique separation selectivity compared to Phenyl-, C8-, and C18-stationary phases, and high efficiency for an expanding number of structurally diverse compounds. (C) 2022 Elsevier B.V. All rights reserved.
Permanent Link: http://hdl.handle.net/11104/0329802