Number of the records: 1
Genomics of Trypanosomatidae: Where We Stand and What Needs to Be Done?
- 1.0555246 - BC 2022 RIV CH eng J - Journal Article
Yurchenko, V. - Butenko, Anzhelika - Kostygov, A.Y.
Genomics of Trypanosomatidae: Where We Stand and What Needs to Be Done?
Pathogens. Roč. 10, č. 9 (2021), č. článku 1124. E-ISSN 2076-0817
R&D Projects: GA MŠMT(CZ) EF16_019/0000759; GA ČR(CZ) GA20-07186S; GA ČR(CZ) GA21-09283S
Institutional support: RVO:60077344
Keywords : candidatus kinetoplastibacterium * herpetomonas-samuelpessoai * leishmania-donovani * minicircle genome * blood-stream * parasite * diversity * lipophosphoglycan * phytomonas * n. * trypanosomatids * next-generation sequencing * genomics
OECD category: Microbiology
Impact factor: 4.531, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-0817/10/9/1124
Trypanosomatids are easy to cultivate and they are (in many cases) amenable to genetic manipulation. Genome sequencing has become a standard tool routinely used in the study of these flagellates. In this review, we summarize the current state of the field and our vision of what needs to be done in order to achieve a more comprehensive picture of trypanosomatid evolution. This will also help to illuminate the lineage-specific proteins and pathways, which can be used as potential targets in treating diseases caused by these parasites.
Permanent Link: http://hdl.handle.net/11104/0329771
Number of the records: 1