Nitrate signaling promotes plant growth by upregulating gibberellin biosynthesis and destabilization of DELLA proteins

0553400 - ÚEB 2022 RIV GB eng J - Journal Article
Camut, L. - Gallova, B. - Jilli, L. - Sirlin-Josserand, M. - Carrera, E. - Sakvarelidze-Achard, L. - Ruffel, S. - Krouk, G. - Thomas, S. G. - Hedden, Peter - Phillips, A. L. - Davière, J. M. - Achard, P.
Nitrate signaling promotes plant growth by upregulating gibberellin biosynthesis and destabilization of DELLA proteins.
Current Biology. Roč. 31, č. 22 (2021), s. 4971-4982. ISSN 0960-9822. E-ISSN 1879-0445
R&D Projects: GA ČR(CZ) GA18-10349S; GA ČR GA20-17984S; GA MŠMT(CZ) EF16_019/0000738
Institutional support: RVO:61389030
Keywords : Arabidopsis * DELLA proteins * gibberellins * growth * hormone biosynthesis * nitrate * plant development * wheat
OECD category: Plant sciences, botany
Impact factor: 10.900, year: 2021
Method of publishing: Open access
http://doi.org/10.1016/j.cub.2021.09.024

Nitrate, one of the main nitrogen (N) sources for crops, acts as a nutrient and key signaling molecule coordinating gene expression, metabolism, and various growth processes throughout the plant life cycle. It is widely accepted that nitrate-triggered developmental programs cooperate with hormone synthesis and transport to finely adapt plant architecture to N availability. Here, we report that nitrate, acting through its signaling pathway, promotes growth in Arabidopsis and wheat, in part by modulating the accumulation of gibberellin (GA)-regulated DELLA growth repressors. We show that nitrate reduces the abundance of DELLAs by increasing GA contents through activation of GA metabolism gene expression. Consistently, the growth restraint conferred by nitrate deficiency is partially rescued in global-DELLA mutant that lacks all DELLAs. At the cellular level, we show that nitrate enhances both cell proliferation and elongation in a DELLA-dependent andindependent manner, respectively. Our findings establish a connection between nitrate and GA signaling pathways that allow plants to adapt their growth to nitrate availability.
Permanent Link: http://hdl.handle.net/11104/0328345