Synergistic performance of collagen-g-chitosan-glucan fiber biohybrid scaffold with tunable properties

0553177 - ÚMCH 2023 RIV GB eng J - Journal Article
Abdel-Rahman, Rasha M. - Vishakha, V. - Kelnar, Ivan - Jancar, J. - Abdel-Mohsen, Abdellatif M.
Synergistic performance of collagen-g-chitosan-glucan fiber biohybrid scaffold with tunable properties.
International Journal of Biological Macromolecules. Roč. 202, 31 March (2022), s. 671-680. ISSN 0141-8130. E-ISSN 1879-0003
R&D Projects: GA ČR(CZ) GA19-06065S
Institutional support: RVO:61389013
Keywords : hybrid scaffolds * collagen * chitosan-glucan fiber
OECD category: Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics
Impact factor: 8.2, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0141813022000058?via%3Dihub

Hybrid biocomposite scaffolds (HBS) that serve as a carrier for cell proliferation and differentiation are increasingly used for tissue regeneration. 3D hybrid scaffold based on collagen-grafted-chitosan-glucan fiber (CO-g-CGF-HBS) was prepared by freeze-drying technique. The swelling percentage, hydrolytic stability, and modulus of elasticity of HBS were enhanced after the chemical modification of CO with CGF. Pore size and porosity of HBS were decreased with an increased CGF ratio. HBS exhibits a higher reduction rate against different types of bacteria compared with a control sample. Thus, chemical modification of CO with different ratios of CGF significantly improved the physicochemical, antibacterial properties of HBS.
Permanent Link: http://hdl.handle.net/11104/0328447