Sparse Evidence for Giardia intestinalis, Cryptosporidium spp. and Microsporidia Infections in Humans, Domesticated Animals and Wild Nonhuman Primates Sharing a Farm-Forest Mosaic Landscape in Western Uganda

0552997 - BC 2022 RIV CH eng J - Journal Article
Cibot, M. - McLennan, M. R. - Kváč, Martin - Sak, Bohumil - Asiimwe, C. - Petrželková, Klára
Sparse Evidence for Giardia intestinalis, Cryptosporidium spp. and Microsporidia Infections in Humans, Domesticated Animals and Wild Nonhuman Primates Sharing a Farm-Forest Mosaic Landscape in Western Uganda.
Pathogens. Roč. 10, č. 8 (2021), č. článku 933. E-ISSN 2076-0817
R&D Projects: GA ČR(CZ) GA21-23773S; GA ČR(CZ) GA20-10706S
Institutional support: RVO:60077344
Keywords : impenetrable national-park * gorilla-gorilla-beringei * cuniculi genotype-iii * mountain gorillas * enterocytozoon-bieneusi * molecular epidemiology * encephalitozoon spp. * habituated gorillas * enteric parasites * great apes * Giardia * Cryptosporidium * microsporidia * non-human primates * humans * domestic animals * anthropogenic disturbance * coproantigen * pcr * Uganda
OECD category: Veterinary science
Impact factor: 4.531, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-0817/10/8/933

Zoonotic pathogen transmission is considered a leading threat to the survival of non-human primates and public health in shared landscapes. Giardia spp., Cryptosporidium spp. and Microsporidia are unicellular parasites spread by the fecal-oral route by environmentally resistant stages and can infect humans, livestock, and wildlife including non-human primates. Using immunoassay diagnostic kits and amplification/sequencing of the region of the triosephosphate isomerase, small ribosomal subunit rRNA and the internal transcribed spacer genes, we investigated Giardia, Cryptosporidium, and microsporidia infections, respectively, among humans, domesticated animals (livestock, poultry, and dogs), and wild nonhuman primates (eastern chimpanzees and black and white colobus monkeys) in Bulindi, Uganda, an area of remarkably high human-animal contact and spatial overlap. We analyzed 137 fecal samples and revealed the presence of G. intestinalis assemblage B in two human isolates, G. intestinalis assemblage E in one cow isolate, and Encephalitozoon cuniculi genotype II in two humans and one goat isolate. None of the chimpanzee and colobus monkey samples were positive for any of the screened parasites. Regular distribution of antiparasitic treatment in both humans and domestic animals in Bulindi could have reduced the occurrence of the screened parasites and decreased potential circulation of these pathogens among host species.
Permanent Link: http://hdl.handle.net/11104/0328050