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Lipophosphonoxins of second generation, and their use
- 1.0552760 - ÚOCHB 2022 RIV eng P - Patent Document
Rejman, Dominik - Pohl, Radek - Zborníková, Eva - Krásný, Libor - Látal, T. - Kolář, M.
Lipophosphonoxins of second generation, and their use.
2021. Owner: Ústav organické chemie a biochemie AV ČR, v. v. i. - Mikrobiologický ústav AV ČR, v. v. i. - TRIOS, spol. s r. o. Date of the patent acceptance: 05.10.2021. Patent Number: US11135237
R&D Projects: GA TA ČR TA02010035
Institutional support: RVO:61388963 ; RVO:61388971
Keywords : antibacterial * lipophosphonoxin * chemotherapeutic
OECD category: Medicinal chemistry
https://worldwide.espacenet.com/patent/search/family/058668694/publication/US11135237B2?q=US11135237
Lipophosphonoxins of general Formula I are described, in which R1 is C8-C22, preferably C10-C18 and more preferably C12-C16 alkyl, or hexadecyloxypropyl, tetradecyloxypropyl, tetradecyloxyethyl or hexadecyloxyethyl, R2 is uracil, thymine, or cytosine, and R3 is selected from a group which contains compounds of general formulas II and III.
Permanent Link: http://hdl.handle.net/11104/0328192
Number of the records: 1