Discovery of New Trichophyton Members, T. persicum and T. spiraliforme spp. nov., as a Cause of Highly Inflammatory Tinea Cases in Iran and Czechia

0550052 - MBÚ 2022 RIV US eng J - Journal Article
Čmoková, Adéla - Rezaei-Matehkolaei, A. - Kuklová, I. - Kolařík, Miroslav - Shamsizadeh, F. - Ansari, S. - Gharaghani, M. - Minovská, V. - Najafzadeh, M. J. - Nouripour-Sisakht, S. - Yaguchi, T. - Zomorodian, K. - Zarrinfar, H. - Hubka, Vít
Discovery of New Trichophyton Members, T. persicum and T. spiraliforme spp. nov., as a Cause of Highly Inflammatory Tinea Cases in Iran and Czechia.
Microbiology Spectrum. Roč. 9, č. 2 (2021), č. článku e00284-21. ISSN 2165-0497. E-ISSN 2165-0497
R&D Projects: GA MZd(CZ) NU21-05-00681
Institutional support: RVO:61388971
Keywords : dermatophytosis * molecular epidemiology * multigene phylogeny * skin mycoses * Trichophyton benhamiae complex * zoonotic infections * zoophilic dermatophytes
OECD category: Microbiology
Impact factor: 9.043, year: 2021
Method of publishing: Open access
https://journals.asm.org/doi/epub/10.1128/Spectrum.00284-21

Pathogens from the Trichophyton benhamiae complex are one of the most important causes of animal mycoses with significant zoonotic potential. In light of the recently revised taxonomy of this complex, we retrospectively identified 38 Trichophyton isolates that could not be resolved into any of the existing species. These strains were isolated from Iranian and Czech patients during molecular epidemiological surveys on dermatophytosis and were predominantly associated with highly inflammatory tinea corporis cases, suggesting possible zoonotic etiology. Subsequent phylogenetic (4 markers), population genetic (10 markers), and phenotypic analyses supported recognition of two novel species. The first species, Trichophyton persicum sp. nov., was identified in 36 cases of human dermatophytosis and one case of feline dermatophytosis, mainly in Southern and Western Iran. The second species, Trichophyton spiraliforme sp. nov., is only known from a single case of tinea corporis in a Czech patient who probably contracted the infection from a dog. Although the zoonotic sources of infections summarized in this study are very likely, little is known about the host spectrum of these pathogens. Awareness of these new pathogens among clinicians should refine our knowledge about their poorly explored geographic distribution.
Permanent Link: http://hdl.handle.net/11104/0325903