CBD is not converted to THC in rats: A framework interpretation and discussion.

0550036 - ÚCHP 2022 RIV NL eng O - Others
Vacek, J. - Papoušková, B. - Polanská, H. - Hönigová, K. - Storch, Jan - Babula, P. - Masařík, M.
CBD is not converted to THC in rats: A framework interpretation and discussion.
2021. European Neuropsychopharmacology. Elsevier. Roč. 50, SEP 2021 (2021), s. 135-136. ISSN 0924-977X. E-ISSN 1873-7862
Institutional support: RVO:67985858
Keywords : cannabidiol * dronabinol * biotransformation
OECD category: Biochemistry and molecular biology
Method of publishing: Open access with time embargo

Cannabidiol (CBD) is a non-psychotropic exogenous cannabinoid that is an active component in a number of topical and oral preparations. The pharmacological potential of CBD is determined by its anti-inflammatory and immuno- or neuromodulatory activities. This natural terpenoid is widely used today, and therefore more attention is now paid to examining its safety after the administration of high doses (Epidiolex) and also after low-dose chronic exposure, e.g. in the form of food supplements. CBD is therefore a molecule that has recently gained a great deal of scientific interest, both at the level of basic research and industrial development.
Permanent Link: http://hdl.handle.net/11104/0325893