Green synthesis of bimetallic ZnO-CuO nanoparticles and their cytotoxicity properties

0549736 - ÚMCH 2022 RIV GB eng J - Journal Article
Cao, Y. - Dhahad, H. A. - El-Shorbagy, M. A. - Alijani, H. Q. - Zakeri, M. - Heydari, A. - Bahonar, E. - Šlouf, Miroslav - Khatami, M. - Naderifar, M. - Iravani, S. - Khatami, S. - Dehkordi, F. F.
Green synthesis of bimetallic ZnO-CuO nanoparticles and their cytotoxicity properties.
Scientific Reports. Roč. 11, č. 1 (2021), č. článku 23479. ISSN 2045-2322. E-ISSN 2045-2322
Institutional support: RVO:61389013
Keywords : green synthesis * bimetallic nanoparticles * anticancer activity
OECD category: Polymer science
Impact factor: 4.997, year: 2021
Method of publishing: Open access
https://www.nature.com/articles/s41598-021-02937-1

In this study, a simple and green strategy was reported to prepare bimetallic nanoparticles (NPs) by the combination of zinc oxide (ZnO) and copper oxide (CuO) using Sambucus nigra L. extract. The physicochemical properties of these NPs such as crystal structure, size, and morphology were studied by X-ray diffraction (XRD), field emission gun scanning electron microscopy (FEG-SEM), and transmission electron microscopy (TEM). The results suggested that these NPs contained polygonal ZnO NPs with hexagonal phase and spherical CuO NPs with monoclinic phase. The anticancer activity of the prepared bimetallic NPs was evaluated against lung and human melanoma cell lines based on MTT assay. As a result, the bimetallic ZnO/CuO NPs exhibited high toxicity on melanoma cancer cells while their toxicity on lung cancer cells was low.
Permanent Link: http://hdl.handle.net/11104/0325781