Dosimetric Optimization of a Laser-Driven Irradiation Facility Using the G4-ELIMED Application

0549657 - FZÚ 2022 RIV CH eng J - Journal Article
Barba, S. M. - Schillaci, Francesco - Catalano, R. - Petringa, Giada - Margarone, Daniele - Cirrone, G. A. P.
Dosimetric Optimization of a Laser-Driven Irradiation Facility Using the G4-ELIMED Application.
Applied Sciences-Basel. Roč. 11, č. 21 (2021), č. článku 9823. E-ISSN 2076-3417
R&D Projects: GA MŠMT EF16_019/0000789
Grant - others:OP VVV - ADONIS(XE) CZ.02.1.01/0.0/0.0/16_019/0000789
Research Infrastructure: ELI Beamlines III - 90141
Institutional support: RVO:68378271
Keywords : Monte Carlo simulations * Geant4 * laser-accelerated ion beams
OECD category: Particles and field physics
Impact factor: 2.838, year: 2021
Method of publishing: Open access

ELIMED has been developed and installed at ELI beamlines as a part of the ELIMAIA beamline to transport, monitor, and use laser-driven ion beams suitable for multidisciplinary applications, including biomedical ones. This paper aims to investigate the feasibility to perform radiobiological experiments using laser-accelerated proton beams with intermediate energies (up to 30 MeV). To reach this goal, we simulate a proton source based on experimental data like the ones expected to be available in the first phase of ELIMED commissioning by using the G4-ELIMED application (an application based on the Geant4 toolkit that simulates the full ELIMED beamline). This allows the study of transmission efficiency and the final characteristics of the proton beam at the sample irradiation point. The Energy Selector System is used as an active energy modulator to obtain the desired beam features in a relatively short irradiation time (around 6 min).
Permanent Link: http://hdl.handle.net/11104/0325626